Coordinated by Community Partners, activities during the weekend are organized by the Greenville School District and local nonprofits like the Friends of the Library, the Greenville Rotary, Boy and Girl Scout groups, local churches, the American Legion and others.

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With the help of the Town of Greenville and local businesses, Greenville Day 2021 will include a town wide yard sale and free fireworks in the evening in Vanderbilt Park consistent with COVID social distancing recommendations. It will also include the auction of the fiberglass ducks on display this summer around town in the North Barn in Vanderbilt Park.